Job Description

Cytokinetics seeks an Associate Scientist to support pharmacology research for cardiac muscle dysfunction programs. The role involves designing and executing in vivo studies, managing animal cohorts, and collaborating with cross-functional teams to advance preclinical compounds toward development.

Responsibilities

• Design, execute, and manage in vivo pharmacology studies with biochemical and molecular assays for cardiac therapeutics
• Oversee animal study cohorts including scheduling, dosing, monitoring, and vivarium coordination with IACUC compliance
• Quantify and interpret disease biomarkers and target engagement through functional and molecular endpoints
• Collaborate with discovery, DMPK, and translational teams on study design, data interpretation, and advancement decisions
• Document experimental methods, manage datasets, and prepare data summaries and presentations for team meetings

Requirements

• BS in Biology, Physiology, Pharmacology, or related field with 8+ years hands-on research experience, or MS with 6+ years
• Demonstrated proficiency in rodent handling and dosing via multiple administration routes
• Extensive experience with biochemical and molecular assays: Western blotting, qPCR, immunohistochemistry, enzyme assays
• Experience with cardiac functional assessments such as echocardiography or blood pressure measurement
• Ability to analyze complex datasets and communicate findings in written and oral formats
• Prior experience in pharmaceutical or biotechnology setting strongly preferred
• Mammalian cell culture or primary cardiomyocyte handling experience a plus

Compensation: $121,500-$141,750 base per year

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